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Error Code 42 x x x x
(example - 42:0:9001:3858:101)
"The game client is unable to gain access to the log-in server at this time. This is most commonly caused by firewall or router settings, security applications, or connecting through a campus network. For additional support, please visit http://support.guildwars2.com."
If you are running security software such as Norton, AVAST, AVG, or McAfee, please try temporarily disabling the software. If this does not work, you might also try adjusting the 'security' setting within the firewall settings. Lowering this setting to 'medium' or 'low' will often clear up connection issues.

In the event that adjusting the security settings does not resolve the issue, please try temporarily uninstalling the security software completely. If this does resolve the issue, please contact the software manufacturer for instructions on how to configure it correctly if you wish to reinstall it.
In addition, Guild Wars 2 requires TCP ports 80, 443, 6112 and port 6600 be fully unrestricted and accessible, both inbound and outbound. For further information about opening ports or port forwarding, you can visit the following website: http://www.portforward.com Please note, this site is not affiliated with or supported by NCsoft or ArenaNet.
If you are connecting to Guild Wars 2 while on a campus, military, or business network, please check with your network's administrator to verify that these ports are fully opened and unrestricted. If you are on a home Local Area Network (LAN), you will want to make sure that your network's hardware is properly configured.